LY108742

Modify Date: 2025-08-25 16:15:30

Use of LY108742

LY108742 is a 5-HT2 receptor antagonist, with IC50 values of 9.3 nM (Rat), 57.2 nM (Pig), 56.8 nM (Monkey)[1].

Name	(8β)-1,6-dimethylergoline-8-carboxylic acid, [R-(R,R)]-2-hydroxy-1-methylpropyl ester
Synonym	More Synonyms

Description	LY108742 is a 5-HT2 receptor antagonist, with IC50 values of 9.3 nM (Rat), 57.2 nM (Pig), 56.8 nM (Monkey)[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. D L Nelson, et al. Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines. J Pharmacol Exp Ther. 1993 Jun;265(3):1272-9.

ERGOLINE-8-CARBOXYLICACID, 1,6-DIMETHYL-, 2-HYDROXY-1-METHYLPROPYL ESTER

(8β)-1,6-dimethylergoline-8-carboxylic acid,(R-(R*,R*))-2-hydroxy-1-methylpropyl ester