150196-69-3

150196-69-3 structure

Name: LY108742
Chemical Name: (8β)-1,6-dimethylergoline-8-carboxylic acid, [R-(R*,R*)]-2-hydroxy-1-methylpropyl ester
CAS Number: 150196-69-3
Molecular Formula: C₂₁H₂₈N₂O₃
Molecular Weight: 356.45900
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2017-07-13 13:59:40
Modify Date: 2024-03-26 15:11:18
LY108742 is a 5-HT2 receptor antagonist, with IC50 values of 9.3 nM (Rat), 57.2 nM (Pig), 56.8 nM (Monkey)[1].

Name	(8β)-1,6-dimethylergoline-8-carboxylic acid, [R-(R,R)]-2-hydroxy-1-methylpropyl ester
Synonyms	ERGOLINE-8-CARBOXYLICACID, 1,6-DIMETHYL-, 2-HYDROXY-1-METHYLPROPYL ESTER (8β)-1,6-dimethylergoline-8-carboxylic acid,(R-(R,R))-2-hydroxy-1-methylpropyl ester

Description	LY108742 is a 5-HT2 receptor antagonist, with IC50 values of 9.3 nM (Rat), 57.2 nM (Pig), 56.8 nM (Monkey)[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. D L Nelson, et al. Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines. J Pharmacol Exp Ther. 1993 Jun;265(3):1272-9.