TWIK-1/TREK-1-IN-2

Modify Date: 2024-01-16 13:06:25

TWIK-1/TREK-1-IN-2 Structure
TWIK-1/TREK-1-IN-2 structure
 Common Name TWIK-1/TREK-1-IN-2
CAS Number 1440532-32-0 Molecular Weight 386.45
Density N/A Boiling Point N/A
Molecular Formula C20H29F3N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TWIK-1/TREK-1-IN-2


TWIK-1/TREK-1-IN-2 (Compound 2g) is a TWIK-1/TREK-1 inhibitor. TWIK-1/TREK-1-IN-2 inhibits TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50s of 10.13 μM and 15.5 μM. TWIK-1/TREK-1-IN-2 is an antidepressant[1].

 Names

Name TWIK-1/TREK-1-IN-2

 TWIK-1/TREK-1-IN-2 Biological Activity

Description TWIK-1/TREK-1-IN-2 (Compound 2g) is a TWIK-1/TREK-1 inhibitor. TWIK-1/TREK-1-IN-2 inhibits TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50s of 10.13 μM and 15.5 μM. TWIK-1/TREK-1-IN-2 is an antidepressant[1].
Related Catalog
References

[1]. Lee EH, et al. Novel potent blockers for TWIK-1/TREK-1 heterodimers as potential antidepressants. Biomed Pharmacother. 2023 Sep;165:115139.  

 Chemical & Physical Properties

Molecular Formula C20H29F3N2O2
Molecular Weight 386.45
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Chemsrc provides TWIK-1/TREK-1-IN-2(CAS#:1440532-32-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of TWIK-1/TREK-1-IN-2 are included as well.>> amp version: TWIK-1/TREK-1-IN-2

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