Insulin(human)
Insulin(human) structure
|
Common Name | Insulin(human) | ||
|---|---|---|---|---|
| CAS Number | 11061-68-0 | Molecular Weight | 5807.58 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C257H383N65O77S6 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Insulin(human)Insulin(human) is a peptide hormone that regulates the level of sugar (glucose) in the blood and that is produced by the beta cells of the pancreatic islets. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Insulin (human) |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Insulin(human) is a peptide hormone that regulates the level of sugar (glucose) in the blood and that is produced by the beta cells of the pancreatic islets. |
|---|---|
| Related Catalog | |
| In Vitro | The human insulin gene contains two intervening sequences, one is within the region transcribed into the 5'-untranslated segment of the mRNA and the other interrupts the C-peptide encoding region[1]. Human insulin is commonly used to treat type 2 diabetes[2]. |
| References |
[1]. Bell GI, et al. Sequence of the human insulin gene. Nature. 1980 Mar 6;284(5751):26-32. |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C257H383N65O77S6 |
|---|---|
| Molecular Weight | 5807.58 |
| Appearance of Characters | Solution |
| InChIKey | PBGKTOXHQIOBKM-FHFVDXKLSA-N |
| SMILES | CCC(C)C(NC(=O)CN)C(=O)NC(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(N)=O)C(=O)NC1CSSCC2NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CSSCC(NC(=O)C(CC(C)C)NC(=O)C(Cc3c[nH]cn3)NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)Cc3ccccc3)C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(Cc3c[nH]cn3)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(Cc3ccccc3)C(=O)NC(Cc3ccccc3)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(C(=O)N3CCCC3C(=O)NC(CCCCN)C(=O)NC(C(=O)O)C(C)O)C(C)O)CSSCC(C(=O)NC(CC(N)=O)C(=O)O)NC(=O)C(Cc3ccc(O)cc3)NC(=O)C(CC(N)=O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(Cc3ccc(O)cc3)NC(=O)C(CC(C)C)NC(=O)C(CO)NC2=O)NC1=O)C(C)C |
| Storage condition | 2-8°C |
| Water Solubility | Soluble up to 10mg/ml in pH <3 or in the presence of surfactants. Adjusting pH with a volatile acid (such as formic acid) prior to dry down will allow the product to be re-dissolved in water. |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | NM8900250 |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Intracellular Ca(2+)-handling differs markedly between intact human muscle fibers and myotubes.
Skelet. Muscle 5 , 26, (2015) In skeletal muscle, intracellular Ca(2+) is an important regulator of contraction as well as gene expression and metabolic processes. Because of the difficulties to obtain intact human muscle fibers, ... |
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LipiD-QuanT: a novel method to quantify lipid accumulation in live cells.
J. Lipid Res. 56 , 2206-16, (2015) Lipid droplets (LDs) are the main storage organelles for triglycerides. Elucidation of lipid accumulation mechanisms and metabolism are essential to understand obesity and associated diseases. Adipoge... |
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Autophagosome-lysosome fusion is independent of V-ATPase-mediated acidification.
Nat. Commun. 6 , 7007, (2015) The ATP-dependent proton pump V-ATPase ensures low intralysosomal pH, which is essential for lysosomal hydrolase activity. Based on studies with the V-ATPase inhibitor BafilomycinA1, lysosomal acidifi... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| MFCD00131380 |
| Oral-lyn |
| Penfil R |
| Ultraphane |
| EINECS 234-279-7 |
| Umulin |
| Velosulin HM |
| ORMD 0801 |
| Insulin(human) |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the safety information for Insulin (human)? |
| A: Safety information for Insulin (human): 22-24/25. |
| Q: What is the molecular formula of Insulin (human)? |
| A: Molecular formula of Insulin (human) is C257H383N65O77S6. |
| Q: What are the storage conditions for Insulin (human)? |
| A: Storage conditions for Insulin (human): 2-8°C. |
| Q: How is the water solubility of Insulin (human)? |
| A: Water solubility of Insulin (human): Soluble up to 10mg/ml in pH <3 or in the presence of surfactants. Adjusting pH with a volatile acid (such as formic acid) prior to dry down will allow the product to be re-dissolved in water. |
| Q: What are the uses of Insulin (human)? |
| A: Main uses of Insulin (human): Insulin(human) is a peptide hormone that regulates the level of sugar (glucose) in the blood and that is produced by the beta cells of the pancreatic islets. |
| Q: What is the CAS number of Insulin (human)? |
| A: CAS number of Insulin (human) is 11061-68-0. |
| Q: What is the InChIKey of Insulin (human)? |
| A: InChIKey of Insulin (human) is PBGKTOXHQIOBKM-FHFVDXKLSA-N. |
| Q: What is the English name of Insulin (human)? |
| A: The English name of Insulin (human) is Insulin (human). |
| Q: What is the molecular weight of Insulin (human)? |
| A: Molecular weight of Insulin (human) is 5807.58. |
| Q: What English synonyms does Insulin (human) have? |
| A: English synonyms of Insulin (human): MFCD00131380, Oral-lyn, Penfil R, Ultraphane, EINECS 234-279-7, Umulin, Velosulin HM, ORMD 0801, Insulin(human). |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Henan Tianfu Chemical Co., Ltd. |