Amino-PEG4-CH2COOH
Amino-PEG4-CH2COOH structure
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Common Name | Amino-PEG4-CH2COOH | ||
|---|---|---|---|---|
| CAS Number | 195071-49-9 | Molecular Weight | 251.27700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H21NO6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Amino-PEG4-CH2COOHAmino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. |
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| Related Catalog | |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2]. |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C10H21NO6 |
|---|---|
| Molecular Weight | 251.27700 |
| Exact Mass | 251.13700 |
| PSA | 100.24000 |
| InChIKey | NPRAKTLKDKKZAV-UHFFFAOYSA-N |
| SMILES | NCCOCCOCCOCCOCC(=O)O |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~82%
Amino-PEG4-CH2COOH CAS#:195071-49-9 |
| Literature: Bogdan, Niculina D.; Matache, Mihaela; Meier, Veronika M.; Dobrotae, Cristian; Dumitru, Ioana; Roiban, Gheorghe D.; Funeriu, Daniel P. Chemistry - A European Journal, 2010 , vol. 16, # 7 p. 2170 - 2180 |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 14-amino-3,6,9,12-tetraoxa-1-tetradecanoic acid |
| 3,6,9,12-Tetraoxatetradecanoic acid,14-amino |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular weight of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid? |
| A: Molecular weight of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid is 251.27700. |
| Q: What are the uses of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid? |
| A: Main uses of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid: Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. |
| Q: What is the InChIKey of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid? |
| A: InChIKey of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid is NPRAKTLKDKKZAV-UHFFFAOYSA-N. |
| Q: What is the SMILES notation of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid? |
| A: SMILES notation of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid is NCCOCCOCCOCCOCC(=O)O. |
| Q: What English synonyms does 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid have? |
| A: English synonyms of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid: 14-amino-3,6,9,12-tetraoxa-1-tetradecanoic acid, 3,6,9,12-Tetraoxatetradecanoic acid,14-amino. |
| Q: What is the Chinese name of 195071-49-9? |
| A: Chinese name of 195071-49-9 is Amino-PEG4-CH2COOH. |
| Q: What is the English name of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid? |
| A: The English name of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid is 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid. |
| Q: What is the polar surface area (PSA) of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid? |
| A: Polar surface area (PSA) of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid is 100.24000. |
| Q: What is the CAS number of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid? |
| A: CAS number of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid is 195071-49-9. |
| Q: What is the molecular formula of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid? |
| A: Molecular formula of 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid is C10H21NO6. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |