2-di-1-asp
2-di-1-asp structure
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Common Name | 2-di-1-asp | ||
|---|---|---|---|---|
| CAS Number | 2156-29-8 | Molecular Weight | 366.24000 | |
| Density | 1.091g/cm3 | Boiling Point | 397.8℃at 760 mmHg | |
| Molecular Formula | C16H19IN2 | Melting Point | 280ºC (dec.)(lit.) | |
| MSDS | USA | Flash Point | 179.3℃ | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 2-di-1-asp2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA[1]. |
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| Related Catalog | |
| In Vitro | 2-Di-1-ASP (Compound 18a) displays significant fluorescence enhancements in the presence of G-quadruplex (G4) structures (up to 300-fold), and good selectivity with respect to double-stranded DNA. 2-Di-1-ASP shows fluorimetric selectivity for parallel G4-DNA forms (c-kit2, c-kit87up, c-myc)[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.091g/cm3 |
|---|---|
| Boiling Point | 397.8℃at 760 mmHg |
| Melting Point | 280ºC (dec.)(lit.) |
| Molecular Formula | C16H19IN2 |
| Molecular Weight | 366.24000 |
| Flash Point | 179.3℃ |
| Exact Mass | 366.05900 |
| PSA | 7.12000 |
| Vapour Pressure | 1.55E-06mmHg at 25°C |
| Index of Refraction | 1.668 |
| InChIKey | XPOIQAIBZGSIDD-UHFFFAOYSA-M |
| SMILES | CN(C)c1ccc(C=Cc2cccc[n+]2C)cc1.[I-] |
| Water Solubility | DMSO: soluble |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
This table lists relevant public references with title, journal and publication metadata for this compound.
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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Proc. Natl. Acad. Sci. U. S. A. 105 , 9059-64, (2008) The growing resistance to current first-line antimalarial drugs represents a major health challenge. To facilitate the discovery of new antimalarials, we have implemented an efficient and robust high-... |
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Distribution pattern of viable mitochondria in bovine lens epithelial cells.
Dev. Ophthalmol. 26 , 90-6, (1994)
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Live-cell imaging of the cytoskeleton and mitochondrial-cytoskeletal interactions in budding yeast.
Methods Mol. Biol. 586 , 41-68, (2009) This chapter describes labeling methods and optical approaches for live-cell imaging of the cytoskeleton and of a specific organelle-cytoskeleton interaction in budding yeast. |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| D-308 |
| 2-{2-[4-(dimethylamino)phenyl]ethenyl}-1-methylpyridinium iodide |
| 2m2Pm |
| 2-(4-(Dimethylamino)styryl)-N-methylpyridinium |
| MFCD00011980 |
| o-DPD |
| 2-<4-(dimethylamino)styryl>-1-ethylpyridinium iodide |
| 2-(4-(dimethylamino)styryl)-1-methylpyridinium |
| (E)-2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide |
| 2-(4-DIMETHYLAMINOSTYRYL)-1-METHYLPYRIDINIUM IODIDE |
| 2-DI-1-ASP |
| EINECS 218-460-8 |
| 1-METHYL-2-P-DIMETHYLAMINO-STYRYL-PYRIDINIUM-IODIDE |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the English name of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide? |
| A: The English name of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide is 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide. |
| Q: What is the safety information for 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide? |
| A: Safety information for 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide: 26-36. |
| Q: What is the molecular weight of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide? |
| A: Molecular weight of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide is 366.24000. |
| Q: What is the molecular formula of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide? |
| A: Molecular formula of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide is C16H19IN2. |
| Q: What is the InChIKey of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide? |
| A: InChIKey of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide is XPOIQAIBZGSIDD-UHFFFAOYSA-M. |
| Q: What is the SMILES notation of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide? |
| A: SMILES notation of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide is CN(C)c1ccc(C=Cc2cccc[n+]2C)cc1.[I-]. |
| Q: What is the melting point of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide? |
| A: Melting point of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide is 280ºC (dec.)(lit.). |
| Q: What is the boiling point of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide? |
| A: Boiling point of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide is 397.8℃at 760 mmHg. |
| Q: What is the CAS number of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide? |
| A: CAS number of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide is 2156-29-8. |
| Q: How is the water solubility of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide? |
| A: Water solubility of 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide: DMSO: soluble. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |