1-Palmitoyl-2-oleoyl-sn-glycero-3-PC

Modify Date: 2026-07-11 10:59:47

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC Structure
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC structure
Common Name 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
CAS Number 26853-31-6 Molecular Weight 760.076
Density N/A Boiling Point N/A
Molecular Formula C42H82NO8P Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC


1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine
Synonym More Synonyms

 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers[1].
Related Catalog
In Vitro 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC) is a phospholipid containing 16:0 and 18:1 fatty acids at the sn-1 and sn-2 positions, respectively[1].
References

[1]. Moreno MJ, et al. Translocation of phospholipids and dithionite permeability in liquid-ordered and liquid-disordered membranes. Biophys J. 2006 Aug 1;91(3):873-81.

[2]. Ferreira TM, et al. Cholesterol and POPC segmental order parameters in lipid membranes: solid state 1H-13C NMR and MD simulation studies. Phys Chem Chem Phys. 2013 Feb 14;15(6):1976-89.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Molecular Formula C42H82NO8P
Molecular Weight 760.076
Exact Mass 759.577820
PSA 121.00000
LogP 11.42
InChIKey WTJKGGKOPKCXLL-VYOBOKEXSA-N
SMILES CCCCCCCCC=CCCCCCCCC(=O)OC(COC(=O)CCCCCCCCCCCCCCC)COP(=O)([O-])OCC[N+](C)(C)C
Storage condition -20℃

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3.0
HS Code 2923900090

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2923900090
Summary 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles70

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Characterizing the structure of lipodisq nanoparticles for membrane protein spectroscopic studies.

Biochim. Biophys. Acta 1848(1 Pt B) , 329-33, (2015)

Membrane protein spectroscopic studies are challenging due to the difficulty introduced in preparing homogenous and functional hydrophobic proteins incorporated into a lipid bilayer system. Traditiona...

Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections.

Pharm. Res. 32(5) , 1546-56, (2015)

To investigate the suitability of three antimicrobial peptides (AMPs) as cell-penetrating antimicrobial peptides.Cellular uptake of three AMPs (PK-12-KKP, SA-3 and TPk) and a cell-penetrating peptide ...

The cytolytic activity of vaginolysin strictly depends on cholesterol and is potentiated by human CD59.

Toxins (Basel.) 7(1) , 110-28, (2015)

Gardnerella vaginalis produces cytolysin vaginolysin (VLY), which has been suggested to be a contributor to bacterial vaginosis pathogenesis. VLY along with intermedilysin (ILY) from Streptococcus int...

 1-Palmitoyl-2-oleoyl-sn-glycero-3-PCBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Inhibition of fertilization by POPC (40 or 400 nm), measured by number of zona-free e...
Source: ChEMBL
Target: Liposome
External Id: CHEMBL711030
Name: Inhibition of fertilization by POPC (40 or 400 nm), measured by average number of spe...
Source: ChEMBL
Target: Liposome
External Id: CHEMBL711029
Name: Inhibition of fertilization by POPC (40 or 400 nm), measured by number of zona-free e...
Source: ChEMBL
Target: Liposome
External Id: CHEMBL711031
Name: Maximal inhibition of fertilization by POPC (40 or 400 nm); No inhibition
Source: ChEMBL
Target: Liposome
External Id: CHEMBL715246
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

MFCD00043212
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
(2R)-2-[(9Z)-9-Octadecenoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
POPC
EINECS 248-056-7
Ethanaminium, 2-[[hydroxy[(2R)-3-[(1-oxohexadecyl)oxy]-2-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propoxy]phosphinyl]oxy]-N,N,N-trimethyl-, inner salt

 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the uses of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine?
A: Main uses of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine: 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers[1].
Q: What is the molecular weight of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine?
A: Molecular weight of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine is 760.076.
Q: What is the molecular formula of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine?
A: Molecular formula of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine is C42H82NO8P.
Q: What is the CAS number of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine?
A: CAS number of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine is 26853-31-6.
Q: What is the safety information for 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine?
A: Safety information for 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine: S22-S24/25.
Q: What is the polar surface area (PSA) of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine?
A: Polar surface area (PSA) of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine is 121.00000.
Q: What is the InChIKey of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine?
A: InChIKey of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine is WTJKGGKOPKCXLL-VYOBOKEXSA-N.
Q: What is the LogP of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine?
A: LogP of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine is 11.42.
Q: What English synonyms does 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine have?
A: English synonyms of 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine: MFCD00043212, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine, (2R)-2-[(9Z)-9-Octadecenoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate, POPC, EINECS 248-056-7, Ethanaminium, 2-[[hydroxy[(2R)-3-[(1-oxohexadecyl)oxy]-2-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propoxy]phosphinyl]oxy]-N,N,N-trimethyl-, inner salt.
Q: What are the storage conditions for 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine?
A: Storage conditions for 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine: -20℃.

 1-Palmitoyl-2-oleoyl-sn-glycero-3-PCfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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