4-Nitrophenyl β-D-Cellobioside
4-Nitrophenyl β-D-Cellobioside structure
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Common Name | 4-Nitrophenyl β-D-Cellobioside | ||
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| CAS Number | 3482-57-3 | Molecular Weight | 463.39000 | |
| Density | 1.7 g/cm3 | Boiling Point | 795.6ºC at 760 mmHg | |
| Molecular Formula | C18H25NO13 | Melting Point | 249-250ºC | |
| MSDS | Chinese USA | Flash Point | 435ºC | |
Use of 4-Nitrophenyl β-D-Cellobioside4-Nitrophenyl β-D-Cellobioside (p-Nitrophenyl β-D-cellobioside) is a cellotriose analog, a chromogenic substrate for the detection of cellulase activity. Exoglucanases, endoglucanases, and β-glucosidases hydrolyze 4-Nitrophenyl β-D-Cellobioside to yield p-nitrophenol (PNP)[1][2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-Nitrophenyl β-D-cellobioside |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 4-Nitrophenyl β-D-Cellobioside (p-Nitrophenyl β-D-cellobioside) is a cellotriose analog, a chromogenic substrate for the detection of cellulase activity. Exoglucanases, endoglucanases, and β-glucosidases hydrolyze 4-Nitrophenyl β-D-Cellobioside to yield p-nitrophenol (PNP)[1][2]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.7 g/cm3 |
|---|---|
| Boiling Point | 795.6ºC at 760 mmHg |
| Melting Point | 249-250ºC |
| Molecular Formula | C18H25NO13 |
| Molecular Weight | 463.39000 |
| Flash Point | 435ºC |
| Exact Mass | 463.13300 |
| PSA | 224.35000 |
| Index of Refraction | 1.67 |
| InChIKey | IAYJZWFYUSNIPN-KFRZSCGFSA-N |
| SMILES | O=[N+]([O-])c1ccc(OC2OC(CO)C(OC3OC(CO)C(O)C(O)C3O)C(O)C2O)cc1 |
| Storage condition | 2-8°C |
| Water Solubility | methanol: water (2:3): 50 mg/mL, clear, faintly yellow |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29400090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 9 | |
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| DownStream 10 | |
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CAS#:42935-24-0This table lists relevant public references with title, journal and publication metadata for this compound.
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Mechanistic studies of active site mutants of Thermomonospora fusca endocellulase E2.
Biochemistry 38(30) , 9746-51, (1999) Endocellulase E2 from the thermophilic bacterium Thermomonospora fusca is a member of glycosyl-hydrolase family 6 and is active from pH 4 to 10. Enzymes in this family hydrolyze beta-1,4-glycosidic bo... |
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Structural changes of cellobiohydrolase I (1,4-beta-D-glucan-cellobiohydrolase I, CBHI) and PNPC (p-nitrophenyl-beta-D-cellobioside) during the binding process.
Sci. China,. C, Life Sci. 51(5) , 459-69, (2008) Conformational changes to 1,4-beta-D-glucan cellobiohydrolase I (CBHI) in response to its binding with p-nitrophenyl beta-D-cellobioside (PNPC) were analyzed by second-derivative fluorescence spectrom... |
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The competitive inhibition of Trichoderma reesei C30 cellobiohydrolase I by guanidine hydrochloride.
FEBS Lett. 270(1-2) , 143-6, (1990) The p-nitrophenylcellobiosidase (PNPCase) activity of Trichoderma reesei cellobiohydrolase I (CBH I) was competitively inhibited by concentrations of guanidine hydrochloride (Gdn HCl) that did not aff... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Specific activity of the PSI segment in rat intestine
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL792194
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Name: Specific activity of the cecum segment in rat intestine
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL792195
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Name: Specific activity of the DSI segment in rat intestine
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL792193
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Name: Specific activity of the stomach segment in rat intestine
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL794806
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Name: Total activity of the entire contents of cecum segment in rat intestine
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL794584
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Name: Total activity of the entire contents of stomach segment in rat intestine
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL794585
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Name: Total activity of the entire contents of DSI segment in rat intestine
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL794582
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Name: Total activity of the entire contents of PSI segment in rat intestine
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL794583
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-NITROPHENYL-β-D-CELLOBIOSIDE |
| 4-Nitrophenyl β-D-Cellobioside |
| 4-NITROPHENYL-BETA-D-CELLOBIOSIDE |
| 4-Nitrophenyl beta-D-Cellobioside |
| MFCD00069845 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular weight of 4-Nitrophenyl β-D-cellobioside? |
| A: Molecular weight of 4-Nitrophenyl β-D-cellobioside is 463.39000. |
| Q: How is the water solubility of 4-Nitrophenyl β-D-cellobioside? |
| A: Water solubility of 4-Nitrophenyl β-D-cellobioside: methanol: water (2:3): 50 mg/mL, clear, faintly yellow. |
| Q: What is the English name of 4-Nitrophenyl β-D-cellobioside? |
| A: The English name of 4-Nitrophenyl β-D-cellobioside is 4-Nitrophenyl β-D-cellobioside. |
| Q: What is the SMILES notation of 4-Nitrophenyl β-D-cellobioside? |
| A: SMILES notation of 4-Nitrophenyl β-D-cellobioside is O=[N+]([O-])c1ccc(OC2OC(CO)C(OC3OC(CO)C(O)C(O)C3O)C(O)C2O)cc1. |
| Q: What English synonyms does 4-Nitrophenyl β-D-cellobioside have? |
| A: English synonyms of 4-Nitrophenyl β-D-cellobioside: 4-NITROPHENYL-β-D-CELLOBIOSIDE, 4-Nitrophenyl β-D-Cellobioside, 4-NITROPHENYL-BETA-D-CELLOBIOSIDE, 4-Nitrophenyl beta-D-Cellobioside, MFCD00069845. |
| Q: What is the safety information for 4-Nitrophenyl β-D-cellobioside? |
| A: Safety information for 4-Nitrophenyl β-D-cellobioside: S24/25. |
| Q: What is the CAS number of 4-Nitrophenyl β-D-cellobioside? |
| A: CAS number of 4-Nitrophenyl β-D-cellobioside is 3482-57-3. |
| Q: What is the InChIKey of 4-Nitrophenyl β-D-cellobioside? |
| A: InChIKey of 4-Nitrophenyl β-D-cellobioside is IAYJZWFYUSNIPN-KFRZSCGFSA-N. |
| Q: What is the boiling point of 4-Nitrophenyl β-D-cellobioside? |
| A: Boiling point of 4-Nitrophenyl β-D-cellobioside is 795.6ºC at 760 mmHg. |
| Q: What are the storage conditions for 4-Nitrophenyl β-D-cellobioside? |
| A: Storage conditions for 4-Nitrophenyl β-D-cellobioside: 2-8°C. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |