Nodakenin
Nodakenin structure
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Common Name | Nodakenin | ||
|---|---|---|---|---|
| CAS Number | 495-31-8 | Molecular Weight | 408.399 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 635.4±55.0 °C at 760 mmHg | |
| Molecular Formula | C20H24O9 | Melting Point | melting at 216° | |
| MSDS | N/A | Flash Point | 225.4±25.0 °C | |
Use of NodakeninNodakenin is a major coumarin glucoside in the root of Peucedanum decursivum Maxim. Nodakenin inhibits acetylcholinesterase (AChE) activity with an IC50 of 84.7 μM[1][2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Nodakenin |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Nodakenin is a major coumarin glucoside in the root of Peucedanum decursivum Maxim. Nodakenin inhibits acetylcholinesterase (AChE) activity with an IC50 of 84.7 μM[1][2]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 635.4±55.0 °C at 760 mmHg |
| Melting Point | melting at 216° |
| Molecular Formula | C20H24O9 |
| Molecular Weight | 408.399 |
| Flash Point | 225.4±25.0 °C |
| Exact Mass | 408.142029 |
| PSA | 138.82000 |
| LogP | -0.66 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.651 |
| InChIKey | HXCGUCZXPFBNRD-DNLMCPORSA-N |
| SMILES | CC(C)(OC1OC(CO)C(O)C(O)C1O)C1Cc2cc3ccc(=O)oc3cc2O1 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Safety Phrases | 24/25 |
|---|---|
| HS Code | 29389090 |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2-(7-Oxo-2,3-dihydro-7H-furo[3,2-g]chromen-3-yl)-2-propanyl β-D-glucopyranoside |
| 2-(7-Oxo-2,3-dihydro-7H-furo[3,2-g]chromen-3-yl)propan-2-yl β-D-glucopyranoside |
| 2-[1-(b-D-Glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-7H-furo[3,2-g][1]benzopyran-7-one |
| Nodakenetin Glucoside |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the safety information for Nodakenin? |
| A: Safety information for Nodakenin: 24/25. |
| Q: What is the molecular weight of Nodakenin? |
| A: Molecular weight of Nodakenin is 408.399. |
| Q: What is the English name of Nodakenin? |
| A: The English name of Nodakenin is Nodakenin. |
| Q: What is the CAS number of Nodakenin? |
| A: CAS number of Nodakenin is 495-31-8. |
| Q: What is the molecular formula of Nodakenin? |
| A: Molecular formula of Nodakenin is C20H24O9. |
| Q: What is the InChIKey of Nodakenin? |
| A: InChIKey of Nodakenin is HXCGUCZXPFBNRD-DNLMCPORSA-N. |
| Q: What is the melting point of Nodakenin? |
| A: Melting point of Nodakenin is melting at 216°. |
| Q: What are the uses of Nodakenin? |
| A: Main uses of Nodakenin: Nodakenin is a major coumarin glucoside in the root of Peucedanum decursivum Maxim. Nodakenin inhibits acetylcholinesterase (AChE) activity with an IC50 of 84.7 μM[1][2]. |
| Q: What is the polar surface area (PSA) of Nodakenin? |
| A: Polar surface area (PSA) of Nodakenin is 138.82000. |
| Q: What is the LogP of Nodakenin? |
| A: LogP of Nodakenin is -0.66. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| naturewill |