(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol
(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol structure
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Common Name | (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol | ||
|---|---|---|---|---|
| CAS Number | 53732-47-1 | Molecular Weight | 148.202 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 254.8±0.0 °C at 760 mmHg | |
| Molecular Formula | C10H12O | Melting Point | 37-39ºC | |
| MSDS | Chinese USA | Flash Point | 99.9±11.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol1-Tetralol, (S)- is a bioactive chemical. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | (1S)-1,2,3,4-tetrahydronaphthalen-1-ol |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 254.8±0.0 °C at 760 mmHg |
| Melting Point | 37-39ºC |
| Molecular Formula | C10H12O |
| Molecular Weight | 148.202 |
| Flash Point | 99.9±11.0 °C |
| Exact Mass | 148.088821 |
| PSA | 20.23000 |
| LogP | 2.05 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.585 |
| InChIKey | JAAJQSRLGAYGKZ-JTQLQIEISA-N |
| SMILES | OC1CCCc2ccccc21 |
| Storage condition | 0-10°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | QL5075000 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 3 | |
CAS#:529-33-9
CAS#:529-34-0
CAS#:90-15-3
CAS#:447-53-0
CAS#:835893-56-6
CAS#:119-64-2
CAS#:108-05-4
CAS#:108-22-5
CAS#:87248-56-4
CAS#:100-06-1
CAS#:23357-46-2This table lists relevant public references with title, journal and publication metadata for this compound.
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Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17.
J. Med. Chem. 49 , 1818-27, (2006) A set of 28 enantiomers comprising rigid and flexible secondary alcohols was synthesized by the asymmetric Corey-Bakshi-Shibata reduction. The enantiomerically pure alcohols were subjected to enzymati... |
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Factorizing the role of a critical leucine residue in the binding of substrate to human 20alpha-hydroxysteroid dehydrogenase (AKR1C1): molecular modeling and kinetic studies of the Leu308Val mutant enzyme.
Bioorg. Med. Chem. Lett. 20 , 5274-6, (2010) A comparison of the structures and kinetic properties of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) and its mutant enzymes (Leu308Val and Leu308Ala) indicates that Leu308 is a selectivity det... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of UGT2B17
Source: ChEMBL
Target: UDP-glucuronosyltransferase 2B17
External Id: CHEMBL867716
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Name: Ratio of Kcat/Km for human recombinant AKR1C1 Leu308Ala mutant to Kcat/Km for human r...
Source: ChEMBL
Target: Aldo-keto reductase family 1 member C1
External Id: CHEMBL1227782
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Name: Ratio of Kcat/Km for human recombinant AKR1C1 Leu308Val mutant to Kcat/Km for human r...
Source: ChEMBL
Target: Aldo-keto reductase family 1 member C1
External Id: CHEMBL1227781
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Name: Ratio of Km for human recombinant AKR1C1 Leu308Ala mutant to Km for human recombinant...
Source: ChEMBL
Target: Aldo-keto reductase family 1 member C1
External Id: CHEMBL1227780
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Name: Ratio of kcat/km for human recombinant AKR1C1 Leu308Ala mutant expressed in Escherich...
Source: ChEMBL
Target: Aldo-keto reductase family 1 member C1
External Id: CHEMBL1227779
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Name: Activity at human recombinant AKR1C1 Leu308Ala mutant expressed in Escherichia coli J...
Source: ChEMBL
Target: Aldo-keto reductase family 1 member C1
External Id: CHEMBL1227778
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Name: Ratio of Km for human recombinant AKR1C1 Leu308Val mutant to Km for human recombinant...
Source: ChEMBL
Target: Aldo-keto reductase family 1 member C1
External Id: CHEMBL1227777
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Name: Ratio of kcat/km for human recombinant AKR1C1 Leu308Val mutant expressed in Escherich...
Source: ChEMBL
Target: Aldo-keto reductase family 1 member C1
External Id: CHEMBL1227776
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Name: Inhibition of UGT2B7
Source: ChEMBL
Target: UDP-glucuronosyltransferase 2B7
External Id: CHEMBL867715
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Name: Activity at human recombinant AKR1C1 Leu308Val mutant expressed in Escherichia coli J...
Source: ChEMBL
Target: Aldo-keto reductase family 1 member C1
External Id: CHEMBL1227775
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol |
| S-Tetralol |
| (S)-(+)-α-Tetralol |
| (S)-1,2,3,4-Tetrahydronaphthalen-1-ol |
| (1S)-1,2,3,4-Tetrahydronaphthalen-1-ol |
| MFCD00063006 |
| (1S)-1,2,3,4-Tetrahydro-1-naphthalenol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol? |
| A: LogP of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol is 2.05. |
| Q: What English synonyms does (1S)-1,2,3,4-tetrahydronaphthalen-1-ol have? |
| A: English synonyms of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol: (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol, S-Tetralol, (S)-(+)-α-Tetralol, (S)-1,2,3,4-Tetrahydronaphthalen-1-ol, (1S)-1,2,3,4-Tetrahydronaphthalen-1-ol, MFCD00063006, (1S)-1,2,3,4-Tetrahydro-1-naphthalenol. |
| Q: What is the InChIKey of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol? |
| A: InChIKey of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol is JAAJQSRLGAYGKZ-JTQLQIEISA-N. |
| Q: What are the upstream materials of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol? |
| A: Related upstream materials(CAS) of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol: 529-33-9;529-34-0;90-15-3;447-53-0;835893-56-6;119-64-2;108-05-4;108-22-5;87248-56-4;100-06-1. |
| Q: What is the SMILES notation of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol? |
| A: SMILES notation of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol is OC1CCCc2ccccc21. |
| Q: What is the melting point of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol? |
| A: Melting point of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol is 37-39ºC. |
| Q: What is the boiling point of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol? |
| A: Boiling point of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol is 254.8±0.0 °C at 760 mmHg. |
| Q: What is the molecular weight of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol? |
| A: Molecular weight of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol is 148.202. |
| Q: What is the English name of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol? |
| A: The English name of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol is (1S)-1,2,3,4-tetrahydronaphthalen-1-ol. |
| Q: What are the uses of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol? |
| A: Main uses of (1S)-1,2,3,4-tetrahydronaphthalen-1-ol: 1-Tetralol, (S)- is a bioactive chemical. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |