MK-212
MK-212 structure
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Common Name | MK-212 | ||
|---|---|---|---|---|
| CAS Number | 61655-58-1 | Molecular Weight | 235.11400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H12Cl2N4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of MK-212MK-212 (CPP) monohydrochloride is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 monohydrochloride can stimulate phosphoinositide hydrolysis in cerebral cortex[1]. |
Summary: Salt酸MK 212, 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride, CAS number 61655-58-1, molecular formula C8H12Cl2N4, molecular weight 235.11400. Appears as a white to off-white powder. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | MK-212 (CPP) monohydrochloride is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 monohydrochloride can stimulate phosphoinositide hydrolysis in cerebral cortex[1]. |
|---|---|
| Related Catalog | |
| Target |
5-HT1C Receptor 5-HT2 Receptor |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C8H12Cl2N4 |
|---|---|
| Molecular Weight | 235.11400 |
| Exact Mass | 234.04400 |
| PSA | 41.05000 |
| LogP | 1.73540 |
| InChIKey | PFIZGLUIYAZQFU-UHFFFAOYSA-N |
| SMILES | Cl.Clc1cncc(N2CCNCC2)n1 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Codes | T+ |
| Risk Phrases | H301 |
| RIDADR | UN 2811 6.1 / PGIII |
| HS Code | 2933990090 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 0 | |
|---|---|
| DownStream 1 | |
![1-[4-(6-chloropyrazin-2-yl)piperazin-1-yl]ethanone structure](https://image.chemsrc.com/caspic/359/61655-59-2.png)
CAS#:61655-59-2This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Serotonin activates catecholamine neurons in the solitary tract nucleus by increasing spontaneous glutamate inputs.
J. Neurosci. 32(46) , 16530-8, (2012) Serotonin (5-HT) is a critical neurotransmitter in the control of autonomic functions. 5-HT(3) receptors participate in vagal afferent feedback to decrease food intake and regulate cardiovascular refl... |
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Characterizing the effects of 5-HT(2C) receptor ligands on motor activity and feeding behaviour in 5-HT(2C) receptor knockout mice.
Neuropharmacology 57(3) , 259-67, (2009) 5-HT(2C) receptor agonists have considerable therapeutic potential, however there is little in vivo data to compare the potency and selectivity of 5-HT(2C) receptor agonists. Since 5-HT(2C) receptor a... |
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Different serotonin receptor agonists have distinct effects on sound-evoked responses in inferior colliculus.
J. Neurophysiol. 96(5) , 2177-88, (2006) The neuromodulator serotonin has a complex set of effects on the auditory responses of neurons within the inferior colliculus (IC), a midbrain auditory nucleus that integrates a wide range of inputs f... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 6-chloro-2-(piperazinyl)pyrazine hydrochloride |
| 1-(6-Chloro-2-pyrazinyl)piperazine hydrochloride |
| 1-(6-chloropyrazin-2-yl)piperazine hydrochloride |
| Sodium chloride |
| 6-chloro-2-(1-piperazinyl)-pyrazine hydrochloride |
| MK 212 hydrochloride |
| 4-(2chloro-6-pyrazinyl)piperazine hydrochloride |
| MK-212 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride? |
| A: LogP of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride is 1.73540. |
| Q: What is the English name of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride? |
| A: The English name of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride is 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride. |
| Q: What is the polar surface area (PSA) of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride? |
| A: Polar surface area (PSA) of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride is 41.05000. |
| Q: What are the downstream products of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride? |
| A: Related downstream products(CAS) of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride: 61655-59-2. |
| Q: What are the uses of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride? |
| A: Main uses of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride: MK-212 (CPP) monohydrochloride is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 monohydrochloride can stimulate phosphoinositide hydrolysis in cerebral cortex[1]. |
| Q: What is the molecular weight of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride? |
| A: Molecular weight of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride is 235.11400. |
| Q: What is the InChIKey of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride? |
| A: InChIKey of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride is PFIZGLUIYAZQFU-UHFFFAOYSA-N. |
| Q: What English synonyms does 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride have? |
| A: English synonyms of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride: 6-chloro-2-(piperazinyl)pyrazine hydrochloride, 1-(6-Chloro-2-pyrazinyl)piperazine hydrochloride, 1-(6-chloropyrazin-2-yl)piperazine hydrochloride, Sodium chloride, 6-chloro-2-(1-piperazinyl)-pyrazine hydrochloride, MK 212 hydrochloride, 4-(2chloro-6-pyrazinyl)piperazine hydrochloride, MK-212. |
| Q: What is the molecular formula of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride? |
| A: Molecular formula of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride is C8H12Cl2N4. |
| Q: What is the CAS number of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride? |
| A: CAS number of 1-(6-chloro-2-pyrazinyl)-piperazine hydrochloride is 61655-58-1. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |