Fialuridine
Fialuridine structure
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Common Name | Fialuridine | ||
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| CAS Number | 69123-98-4 | Molecular Weight | 372.09 | |
| Density | 2.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C9H10FIN2O5 | Melting Point | 216-217ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of FialuridineFialuridine is a nucleoside analog with antiviral activity[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Fialuridine is a nucleoside analog with antiviral activity[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 2.2±0.1 g/cm3 |
|---|---|
| Melting Point | 216-217ºC |
| Molecular Formula | C9H10FIN2O5 |
| Molecular Weight | 372.09 |
| Exact Mass | 371.961823 |
| PSA | 104.55000 |
| LogP | -0.32 |
| Index of Refraction | 1.685 |
| InChIKey | IPVFGAYTKQKGBM-BYPJNBLXSA-N |
| SMILES | O=c1[nH]c(=O)n(C2OC(CO)C(O)C2F)cc1I |
| Storage condition | Refrigerator |
| Water Solubility | DMSO: soluble5mg/mL, clear (warmed) |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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Fialuridine CAS#:69123-98-4 |
| Literature: RESprotech GmbH Patent: US2010/227834 A1, 2010 ; Location in patent: Page/Page column 18 ; |
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Fialuridine CAS#:69123-98-4 |
| Literature: US4211773 A1, ; |
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Fialuridine CAS#:69123-98-4 |
| Literature: Journal of Organic Chemistry, , vol. 73, # 21 p. 8236 - 8243 |
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Fialuridine CAS#:69123-98-4 |
| Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 40, p. 91 - 93 |
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Fialuridine CAS#:69123-98-4 |
| Literature: Journal of Organic Chemistry, , vol. 50, # 19 p. 3644 - 3647 |
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Fialuridine CAS#:69123-98-4 |
| Literature: Journal of Organic Chemistry, , vol. 50, # 19 p. 3644 - 3647 |
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Fialuridine CAS#:69123-98-4 |
| Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 40, p. 91 - 93 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 6 | |
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| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Improved synthesis of 2'-deoxy-2'-[18F]-fluoro-1-beta-D-arabinofuranosyl-5-iodouracil ([18F]-FIAU).
Nucl. Med. Biol. 37(4) , 439-42, (2010) An improved synthesis of 2'-[(18)F]-fluoro-2'-deoxy-1-beta-D-arabinofuranosyl-5-iodouracil ([(18)F]-FIAU) has been developed. The method utilizes trimethylsilyl trifluoromethanesulfonate (TMSOTf) cata... |
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Imaging of a localized bacterial infection with endogenous thymidine kinase using radioisotope-labeled nucleosides.
Int. J. Med. Microbiol. 302(2) , 101-7, (2012) The importance of noninvasive imaging methods to bacterial infections is widely recognized. To obtain bacterial infection imaging with radioisotope-labeled nucleosides, bacterial thymidine kinase (tk)... |
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Enhanced antitumor effects by combination gene therapy using MDR1 gene shRNA and HSV1-tk in a xenograft mouse model.
Cancer Lett. 291(1) , 83-9, (2010) The use of a novel therapeutic vector containing HSV1-thymidine kinase (HSV1-tk) and a short hairpin RNA for the MDR1 gene (shMDR) was proposed previously. We investigated the antitumor effects in an ... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil |
| 1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione |
| 1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione |
| 1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione |
| Fialuridine |
| 5-Iodo-2'-fluoroarauracil |
| 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione |
| 2'-Deoxy-2'-fluoro-5-iodouridine |
| 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione |
| 1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodouracil |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular formula of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil? |
| A: Molecular formula of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil is C9H10FIN2O5. |
| Q: How is the water solubility of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil? |
| A: Water solubility of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil: DMSO: soluble5mg/mL, clear (warmed). |
| Q: What is the LogP of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil? |
| A: LogP of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil is -0.32. |
| Q: What is the SMILES notation of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil? |
| A: SMILES notation of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil is O=c1[nH]c(=O)n(C2OC(CO)C(O)C2F)cc1I. |
| Q: What are the upstream materials of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil? |
| A: Related upstream materials(CAS) of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil: 97614-45-4;69124-02-3;213136-12-0;97614-43-2;97614-44-3;97614-42-1. |
| Q: What are the uses of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil? |
| A: Main uses of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil: Fialuridine is a nucleoside analog with antiviral activity[1]. |
| Q: What is the melting point of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil? |
| A: Melting point of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil is 216-217ºC. |
| Q: What is the InChIKey of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil? |
| A: InChIKey of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil is IPVFGAYTKQKGBM-BYPJNBLXSA-N. |
| Q: What is the English name of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil? |
| A: The English name of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil is 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil. |
| Q: What is the CAS number of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil? |
| A: CAS number of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil is 69123-98-4. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |