Nile Red

Modify Date: 2026-08-02 16:54:13

Nile Red Structure
Nile Red structure
Common Name Nile Red
CAS Number 7385-67-3 Molecular Weight 318.369
Density 1.2±0.1 g/cm3 Boiling Point 484.7±45.0 °C at 760 mmHg
Molecular Formula C20H18N2O2 Melting Point 203-205 °C(lit.)
MSDS Chinese USA Flash Point 246.9±28.7 °C

 Use of Nile Red


Nile Red is a strongly fluorescent stain in the presence of a hydrophobic environment for the detection of intracellular lipid droplets.

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name nile red dye
Synonym More Synonyms

 Nile Red Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Nile Red is a strongly fluorescent stain in the presence of a hydrophobic environment for the detection of intracellular lipid droplets.
Related Catalog
References

[1]. Greenspan P, et al. Nile red: a selective fluorescent stain for intracellular lipid droplets. J Cell Biol. 1985 Mar;100(3):965-73.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.2±0.1 g/cm3
Boiling Point 484.7±45.0 °C at 760 mmHg
Melting Point 203-205 °C(lit.)
Molecular Formula C20H18N2O2
Molecular Weight 318.369
Flash Point 246.9±28.7 °C
Exact Mass 318.136841
PSA 46.34000
LogP 3.65
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.644
InChIKey VOFUROIFQGPCGE-UHFFFAOYSA-N
SMILES CCN(CC)c1ccc2nc3c4ccccc4c(=O)cc-3oc2c1
Stability Stable. Incompatible with strong oxidizing agents.

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~%

Nile Red Structure

Nile Red

CAS#:7385-67-3

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Literature: Ionescu, Andreea; Godbert, Nicolas; Crispini, Alessandra; Termine, Roberto; Golemme, Attilio; Ghedini, Mauro Journal of Materials Chemistry, 2012 , vol. 22, # 44 p. 23617 - 23626

~24%

Nile Red Structure

Nile Red

CAS#:7385-67-3

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Literature: Park, So-Yeon; Kubota, Yasuhiro; Funabiki, Kazumasa; Shiro, Motoo; Matsui, Masaki Tetrahedron Letters, 2009 , vol. 50, # 10 p. 1131 - 1135

~%

Nile Red Structure

Nile Red

CAS#:7385-67-3

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Literature: Justus Liebigs Annalen der Chemie, , vol. 289, p. 94

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  4

DownStream  1

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles49

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Acoustic Cluster Therapy (ACT)--A novel concept for ultrasound mediated, targeted drug delivery.

Int. J. Pharm. 495 , 1019-27, (2015)

A novel approach for ultrasound (US) mediated drug delivery - Acoustic Cluster Therapy (ACT) - is proposed, and basic characteristics of the ACT formulation are elucidated. The concept comprises admin...

High-fat diet-induced adiposity, adipose inflammation, hepatic steatosis and hyperinsulinemia in outbred CD-1 mice.

PLoS ONE 10(3) , e0119784, (2015)

High-fat diet (HFD) has been applied to a variety of inbred mouse strains to induce obesity and obesity related metabolic complications. In this study, we determined HFD induced development of metabol...

microRNA-320/RUNX2 axis regulates adipocytic differentiation of human mesenchymal (skeletal) stem cells.

Cell Death Dis. 5 , e1499, (2014)

The molecular mechanisms promoting lineage-specific commitment of human mesenchymal (skeletal or stromal) stem cells (hMSCs) into adipocytes (ADs) are not fully understood. Thus, we performed global m...

 Nile RedBioassay

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This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2
Source: NCGC
Target: eyes absent homolog 2 isoform a [Homo sapiens]
External Id: EYA2477
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
Name: Primary cell-based high-throughput screening for identification of compounds that all...
Source: Johns Hopkins Ion Channel Center
Target: MAS-related GPR member X1 [Homo sapiens]
External Id: JHICC_MrgX1_AlloAgonist_Primary
Name: Primary cell-based high-throughput screening for identification of compounds that ant...
Source: Johns Hopkins Ion Channel Center
Target: MAS-related GPR member X1 [Homo sapiens]
External Id: JHICC_MrgX1_Antagonist_Primary
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: High throughput screen for small molecule inhibitors of a hypoxia-regulated fluoresce...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1149-MLP
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Nile Red
9-(Diethylamino)-5H-benzo[a]phenoxazin-5-one
9-(Diethylamino)-5H-benzo(a)phenoxazin-5-one
DCC impregnated tablets
Nile Blue A Oxazone
MFCD00011639
9-(Diethylamino)benzo(a)phenoxazin-5(5H)-one
9-(diethylamino)benzo[a]phenoxazin-5-one
EINECS 230-966-0

 Nile Red | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the boiling point of nile red dye?
A: Boiling point of nile red dye is 484.7±45.0 °C at 760 mmHg.
Q: What English synonyms does nile red dye have?
A: English synonyms of nile red dye: Nile Red, 9-(Diethylamino)-5H-benzo[a]phenoxazin-5-one, 9-(Diethylamino)-5H-benzo(a)phenoxazin-5-one, DCC impregnated tablets, Nile Blue A Oxazone, MFCD00011639, 9-(Diethylamino)benzo(a)phenoxazin-5(5H)-one, 9-(diethylamino)benzo[a]phenoxazin-5-one, EINECS 230-966-0.
Q: What are the upstream materials of nile red dye?
A: Related upstream materials(CAS) of nile red dye: 90-15-3;91-68-9;25953-06-4;135-19-3.
Q: What are the uses of nile red dye?
A: Main uses of nile red dye: Nile Red is a strongly fluorescent stain in the presence of a hydrophobic environment for the detection of intracellular lipid droplets.
Q: What is the polar surface area (PSA) of nile red dye?
A: Polar surface area (PSA) of nile red dye is 46.34000.
Q: What is the LogP of nile red dye?
A: LogP of nile red dye is 3.65.
Q: What is the InChIKey of nile red dye?
A: InChIKey of nile red dye is VOFUROIFQGPCGE-UHFFFAOYSA-N.
Q: What is the CAS number of nile red dye?
A: CAS number of nile red dye is 7385-67-3.
Q: What is the SMILES notation of nile red dye?
A: SMILES notation of nile red dye is CCN(CC)c1ccc2nc3c4ccccc4c(=O)cc-3oc2c1.
Q: What are the downstream products of nile red dye?
A: Related downstream products(CAS) of nile red dye: 569686-05-1.

 Nile Redfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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