Bis-PEG6-acid

Modify Date: 2026-07-15 18:54:34

Bis-PEG6-acid Structure
Bis-PEG6-acid structure
Common Name Bis-PEG6-acid
CAS Number 77855-76-6 Molecular Weight 354.35
Density N/A Boiling Point N/A
Molecular Formula C14H26O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-PEG6-acid


PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name PEG6-(CH2CO2H)2

 Bis-PEG6-acid Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation[1].
Related Catalog
Target

PROTAC linker[1]

References

[1]. Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Molecular Formula C14H26O10
Molecular Weight 354.35
InChIKey DCQRSABUSOYSIY-UHFFFAOYSA-N
SMILES O=C(O)COCCOCCOCCOCCOCCOCC(=O)O

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi

 Bis-PEG6-acid | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the CAS number of PEG6-(CH2CO2H)2?
A: CAS number of PEG6-(CH2CO2H)2 is 77855-76-6.
Q: What is the English name of PEG6-(CH2CO2H)2?
A: The English name of PEG6-(CH2CO2H)2 is PEG6-(CH2CO2H)2.
Q: What is the SMILES notation of PEG6-(CH2CO2H)2?
A: SMILES notation of PEG6-(CH2CO2H)2 is O=C(O)COCCOCCOCCOCCOCCOCC(=O)O.
Q: What is the molecular weight of PEG6-(CH2CO2H)2?
A: Molecular weight of PEG6-(CH2CO2H)2 is 354.35.
Q: What is the InChIKey of PEG6-(CH2CO2H)2?
A: InChIKey of PEG6-(CH2CO2H)2 is DCQRSABUSOYSIY-UHFFFAOYSA-N.
Q: What are the uses of PEG6-(CH2CO2H)2?
A: Main uses of PEG6-(CH2CO2H)2: PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation[1].
Q: What is the molecular formula of PEG6-(CH2CO2H)2?
A: Molecular formula of PEG6-(CH2CO2H)2 is C14H26O10.

 Bis-PEG6-acidfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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