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77855-76-6

77855-76-6 structure
77855-76-6 structure
  • Name: Bis-PEG6-acid
  • Chemical Name: PEG6-(CH2CO2H)2
  • CAS Number: 77855-76-6
  • Molecular Formula: C14H26O10
  • Molecular Weight: 354.35
  • Catalog: Signaling Pathways PROTAC PROTAC
  • Create Date: 2019-08-04 11:22:58
  • Modify Date: 2024-01-08 16:11:21
  • PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation[1].

Name PEG6-(CH2CO2H)2
Description PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation[1].
Related Catalog
Target

PROTAC linker[1]

References

[1]. Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.

Molecular Formula C14H26O10
Molecular Weight 354.35
Hazard Codes Xi