| Name | NS 3763 | CAS# | 70553-45-6 | |
|---|---|---|---|---|
| Price | ¥Inquiry/1g | Purity | 98.9% | |
| Stocking Period |
1 Day | Stock | In Stock |
| Detail
Product Information
NS3763 is a noncompetitive antagonist of GLUK5 receptor. NS3763 displays selectivity for inhibition of domoate-induced increase in intracellular calcium mediated through the GLU(K5) subtype (IC(50) = 1.6 microM) of kainate receptors compared with the GLU(K6) subtype (IC(50) > 30 microM). NS3763 inhibits the GLU(K5)-mediated response in a noncompetitive manner. NS3763 selectively inhibits l-glutamate- and domoate-evoked currents through GLU(K5) receptors in HEK293 cells. |