Name | PROTAC IDO1 Degrader-1 | CAS# | 2488851-89-2 | |
---|---|---|---|---|
Price | $Inquiry/100mg $Inquiry/250mg $Inquiry/1g | Purity | 98.0% | |
Stocking Period |
3 Day | Stock | 3 | |
Product Webpage: | https://www.dcchemicals.com/product_show-PROTAC_IDO1_Degrader-1.html |
Detail
Product Information
PROTAC IDO1 Degrader-1 is the first potent IDO1 (indoleamine 2,3-dioxygenase 1) degrader that hijacks IDO1 to CRBN E3 ligase to introduce IDO1 into UPS and eventually achieve ubiquitination and degradation (DC50=2.84 μM). PROTAC IDO1 Degrader-1 moderately improves the tumor-killing activity of H ER2 CAR-T cells. |