Name | FM-479 | CAS# | 2226521-64-6 | |
---|---|---|---|---|
Price | $1300.0/250mg $750.0/100mg $2600.0/1g | Purity | 98.0% | |
Stocking Period |
3 Day | Stock | 3 | |
Product Webpage: | https://www.dcchemicals.com/product_show-FM-479.html |
Detail
Product Information
FM-479 is the negative control of FM-381 (HY-102046) and has no activity on JAK3 or other kinases. FM-381 is a potent covalent reversible inhibitor of?JAK3?targeting the unique Cys909. FM-381 has an?IC50?of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively. |