常用名 | FM-479 | CAS号 | 2226521-64-6 |
---|---|---|---|
价格 | $1300.0/250mg $750.0/100mg $2600.0/1g | 纯度 | 98.0% |
备货期 | 3天 | 库存 | 3 |
产品网页 | https://www.dcchemicals.com/product_show-FM-479.html |
产品详情(用途,包装等)
FM-479 is the negative control of FM-381 (HY-102046) and has no activity on JAK3 or other kinases. FM-381 is a potent covalent reversible inhibitor of?JAK3?targeting the unique Cys909. FM-381 has an?IC50?of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively. |