Phe-Ala

Modify Date: 2025-08-25 17:40:00

Phe-Ala Structure
Phe-Ala structure
Common Name Phe-Ala
CAS Number 3918-87-4 Molecular Weight 236.26700
Density 1.222g/cm3 Boiling Point 506ºC at 760mmHg
Molecular Formula C12H16N2O3 Melting Point 241℃ (Decomposition)
MSDS Chinese USA Flash Point 259.8ºC

 Use of Phe-Ala


Phenylalanylalanine (H-Phe-Ala-OH) is a dipeptide composed of phenylalanine and alanine. Phenylalanylalanine is an incomplete breakdown product of protein digestion or protein catabolism[1].

 Names

Name (2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]propanoic acid
Synonym More Synonyms

 Phe-Ala Biological Activity

Description Phenylalanylalanine (H-Phe-Ala-OH) is a dipeptide composed of phenylalanine and alanine. Phenylalanylalanine is an incomplete breakdown product of protein digestion or protein catabolism[1].
Related Catalog
References

[1]. Facchin G, et al. Experimental and theoretical studies of copper complexes with isomeric dipeptides as novel candidates against breast cancer. J Inorg Biochem. 2016;162:52‐61.

 Chemical & Physical Properties

Density 1.222g/cm3
Boiling Point 506ºC at 760mmHg
Melting Point 241℃ (Decomposition)
Molecular Formula C12H16N2O3
Molecular Weight 236.26700
Flash Point 259.8ºC
Exact Mass 236.11600
PSA 92.42000
LogP 1.23690
Index of Refraction 1.565
InChIKey MIDZLCFIAINOQN-WPRPVWTQSA-N
SMILES CC(NC(=O)C(N)Cc1ccccc1)C(=O)O
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2924299090

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles22

More Articles
Alkali metal complexes of the dipeptides PheAla and AlaPhe: IRMPD spectroscopy.

ChemPhysChem 9 , 579-589, (2008)

Complexes of PheAla and AlaPhe with alkali metal ions Na(+) and K(+) are generated by electrospray ionization, isolated in the Fourier-transform ion cyclotron resonance (FT-ICR) ion trapping mass spec...

Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-beta3-hAla-NHMe and Ac-beta3-hAla-beta3-hPhe-NHMe.

J. Am. Chem. Soc. 130(14) , 4795-807, (2008)

The conformational preferences and infrared and ultraviolet spectral signatures of two model beta-peptides, Ac-beta3-hPhe-beta3-hAla-NHMe (1) and Ac-beta3-hAla-beta3-hPhe-NHMe (2), have been explored ...

A novel inhibitor of the mammalian peptide transporter PEPT1.

Biochemistry 40(14) , 4454-8, (2001)

This study was initiated to develop inhibitors of the intestinal H(+)/peptide symporter. We provide evidence that the dipeptide derivative Lys[Z(NO(2))]-Pro is an effective competitive inhibitor of ma...

 Phe-AlaBioassay

View more

Name: Inhibition of UBR protein in rabbit reticulocyte lysates assessed as inhibition of Ty...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2344103
Name: Activation of human PEPT1 expressed in MDCK cells
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL863210
Name: Activation of human PEPT1 expressed in MDCK cells relative to Gly-Sar
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL863211
Name: Inhibition of UBR protein in rabbit reticulocyte lysates assessed as inhibition of Ty...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2344563
Name: Binding affinity against membrane transport protein PEPT1 in human Caco-2 cells
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL841787
Name: Affinity against Renal peptide transporter PepT2 in SKPT cells was measured by the in...
Source: ChEMBL
Target: N/A
External Id: CHEMBL801740
Name: Ratio of %GSmax to EC50 for human PEPT1 activation
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL863212
Name: Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK...
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL863213
Name: 50% Inhibitory potency against enkephalinase from mouse striatum.
Source: ChEMBL
Target: Neprilysin
External Id: CHEMBL676649
Name: Concentration required to inhibit the maximum [14C]Gly-Sar uptake by Renal peptide tr...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL801739
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 Synonyms

L-Alanine,N-L-phenylalanyl
Phe-ala
Phenylalanylalanine
L-Phenylalanyl-L-alanine
L-phenylalanine-L-alanine
L-Phe-L-Ala-OH
Phenylalanine-Alanine
L-Phe-L-Ala
H-PHE-ALA-OH
H-Phe-β-Ala-OH
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