Exploring the UDP pocket of LpxC through amino acid analogs

MR Hale, P Hill, S Lahiri, MD Miller, P Ross…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 8 p. 2362 - 2367

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Citation Number: 7

Abstract

... Bioorganic & Medicinal Chemistry Letters. Volume 23, Issue 8, 15 April 2013, Pages 2362–2367. Cover image Cover image. ... The inhibitors discussed in this Letter focus on diversity in the UDP pocket through R 1 variations, we then studied how they impact potency. ...