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Exploring the UDP pocket of LpxC through amino acid analogs

MR Hale, P Hill, S Lahiri, MD Miller, P Ross…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 8 p. 2362 - 2367

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被引用次数: 7

摘要

... Bioorganic & Medicinal Chemistry Letters. Volume 23, Issue 8, 15 April 2013, Pages 2362–2367. Cover image Cover image. ... The inhibitors discussed in this Letter focus on diversity in the UDP pocket through R 1 variations, we then studied how they impact potency. ...