Applied and Environmental Microbiology 2008-10-01

Transformation of N-phenylpiperazine by mixed cultures from a municipal wastewater treatment plant.

Carina M Jung, Thomas M Heinze, Joanna Deck, Ruth Strakosha, John B Sutherland

Index: Appl. Environ. Microbiol. 74(19) , 6147-50, (2008)

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Abstract

Samples from a wastewater treatment plant were used as inocula for mixed cultures dosed with N-phenylpiperazine (NPP), a model compound containing the piperazine ring found in many fluoroquinolones. Chemical analyses showed that NPP (50 mg liter(-1)) disappeared in 12 days, with the appearance of a transient metabolite and two nitrosated compounds.