Voprosy Virusologii 2013-01-01

[Estimation of activity of bis-netropsin derivatives based on a model of an experimental cutaneous herpes simplex virus disease of guinea pigs].

V L andronova, S L Grokhovskiĭ, A N Surovaia, G V Gurskiĭ, P G Deriabin, D K L'vov, G A Galegov

Index: Vopr. Virusol. 58(1) , 32-5, (2013)

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Abstract

Using the model of an experimental cutaneous infection of guinea pig males caused by herpes simple virus type 1, it is shown that application of dimerico derivatives of netropsin Lys-bis Nt and 15Lys-bis Nt in the form of polietilenglicol-based ointment suppresses viral infection more effectively than acyclovir.