New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site

N Moss, S Breitfelder, R Betageri, PF Cirillo…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 15 p. 4242 - 4247

Full Text: HTML

Citation Number: 20

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... b Department of Medicinal Chemistry, Boehringer Ingelheim Pharma GmbH and Co. ... and pyrazole containing left hand sides required for the preparation of analogues 16 and 17 relied on the vinamidinium chemistry outlined in Scheme ...

Electrophilic bromination of alkenes, alkynes, and aromatic ...

[Khazaei, Ardeshir; Zolfigol, Mohammad Ali; Kolvari, Eskandar; Koukabi, Nadiya; Soltani, Hamid; Bayani, Leyla Sharaf Synthetic Communications, 2010 , vol. 40, # 19 p. 2954 - 2962]

Palladium-catalyzed monoamination of dihalogenated benzenes

[Larsen, Simon Birkso; Bang-Andersen, Benny; Johansen, Tommy Norskov; Jorgensen, Morten Tetrahedron, 2008 , vol. 64, # 13 p. 2938 - 2950]

Antifouling character of 'active'hybrid xerogel coatings wit...

[Bennett, Stephanie M.; Tang, Ying; McMaster, Danielle; Bright, Frank V.; Detty, Michael R. Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6849 - 6852]

Copper??Catalyzed Amination of Arylboronates with N, N??Dial...

[Angewandte Chemie - International Edition, , vol. 51, # 15 p. 3642 - 3645]

Synthesis of Hindered Anilines: Copper??Catalyzed Electrophi...

[Rucker, Richard P.; Whittaker, Aaron M.; Dang, Hester; Lalic, Gojko Angewandte Chemie - International Edition, 2012 , vol. 51, # 16 p. 3953 - 3956]