New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site

N Moss, S Breitfelder, R Betageri, PF Cirillo…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 15 p. 4242 - 4247

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被引用次数: 20

摘要

... Bioorganic & Medicinal Chemistry Letters. ... b Department of Medicinal Chemistry, Boehringer Ingelheim Pharma GmbH and Co. ... and pyrazole containing left hand sides required for the preparation of analogues 16 and 17 relied on the vinamidinium chemistry outlined in Scheme ...