China Journal of Chinese Materia Medica 2013-05-01

[Chemical constituents of Salvia chinensis].

Jun-Feng Gao, Ling Ding, Peng Zhang, Jian-Xun Liu

Index: Zhongguo Zhong Yao Za Zhi 38(10) , 1556-9, (2013)

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Abstract

Chemical constituents were investigated on the ethyl acetate extract of Salvia chinensis. Compounds were separated and purified by various chromatograhic techniques including silica gel, Sephadex LH-20 and reversed-phase HPLC. Their structures were identified by spectroscopic data analysis. Eleven compounds were isolated and purified and their structures were identified as oresbiusin A(1), ethyl dihydrocaffeate (2), ethyl rosmarinate (3), rosmarinic acid (4), methyl rosmarinate (5), bis (2-ethylhexyl) phthalate (6), salvianol acid C (7), methyl salvianol acid C (8), methyl salvianolate A (9), dimethyl lithospermate B (10), and salvianolic acid A(11). Except for rosmarinic acid, the remaining compounds were isolated from S. chinensis for the first time.