Organic Letters 2005-03-03

PS-COD and PS-9-BBN: polymer-supported reagents for solution-phase parallel synthesis.

Jefferson D Revell, Barbara Dörner, Peter D White, A Ganesan

Index: Org. Lett. 7(5) , 831-3, (2005)

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Abstract

1,5-Cyclooctadiene was deprotonated under LICKOR conditions and reacted with Merrifield resin to afford an immobilized cyclooctadiene in high yield. This polymer is effective as a halogen scavenger, while hydroboration leads to a supported 9-BBN analogue. The latter exhibits similar regioselectivity to 9-BBN in olefin hydroboration. [reaction: see text]