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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Helvetica chimica acta

An Improved Liquid??Phase Synthesis of Simple Alkylpyridines

JI Grayson, R Dinkel

Index: Grayson, J. Ian; Dinkel, Rolf Helvetica Chimica Acta, 1984 , vol. 67, p. 2100 - 2110

Full Text: HTML

Citation Number: 11

Abstract

Abstract The synthesis of pyridines from mixtures of aldehydes or ketones NH 3 in the liquid phase has been reinvestigated, using continuous dosage of the carbonyl components to the reaction mixture. The main product from the reaction of acetaldehyde and formaldehyde is 3-

 Related Synthetic Route
Formaldehyde Structure

50-00-0

Formaldehyde

Butyraldehyde Structure

123-72-8

Butyraldehyde

~53%

3,5-diethylpyridine Structure

699-25-2

3,5-diethylpyridine

Formaldehyde Structure

50-00-0

Formaldehyde

Acetone Structure

67-64-1

Acetone

~9%

2,4,5-Trimethylpyridine Structure

1122-39-0

2,4,5-Trimethyl...

2,3,4-trimethylpyridine Structure

2233-29-6

2,3,4-trimethyl...

Detail
Formaldehyde Structure

50-00-0

Formaldehyde

Propionaldehyde Structure

123-38-6

Propionaldehyde

~0%

Pyridine Structure

110-86-1

Pyridine

2-picoline Structure

109-06-8

2-picoline

Detail
Formaldehyde Structure

50-00-0

Formaldehyde

Propionaldehyde Structure

123-38-6

Propionaldehyde

~47%

Pyridine Structure

110-86-1

Pyridine

2-picoline Structure

109-06-8

2-picoline

Detail
Formaldehyde Structure

50-00-0

Formaldehyde

Acetone Structure

67-64-1

Acetone

~35%

2,4,5-Trimethylpyridine Structure

1122-39-0

2,4,5-Trimethyl...

2,3,4-trimethylpyridine Structure

2233-29-6

2,3,4-trimethyl...

Detail
Formaldehyde Structure

50-00-0

Formaldehyde

ch3cho Structure

75-07-0

ch3cho

Acetone Structure

67-64-1

Acetone

~13%

2,3-Lutidine Structure

583-61-9

2,3-Lutidine

Detail
ch3cho Structure

75-07-0

ch3cho

Acetone Structure

67-64-1

Acetone

~46%

2,4,6-Trimethylpyridine Structure

108-75-8

2,4,6-Trimethyl...

2,6-Dimethyl-3-ethylpyridine Structure

23580-52-1

2,6-Dimethyl-3-...

Detail
ch3cho Structure

75-07-0

ch3cho

Acetone Structure

67-64-1

Acetone

~7%

2,4,6-Trimethylpyridine Structure

108-75-8

2,4,6-Trimethyl...

2,6-Dimethyl-3-ethylpyridine Structure

23580-52-1

2,6-Dimethyl-3-...

Detail
Formaldehyde Structure

50-00-0

Formaldehyde

Propionaldehyde Structure

123-38-6

Propionaldehyde

~0%

Pyridine Structure

110-86-1

Pyridine

2-picoline Structure

109-06-8

2-picoline

Detail
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Syntheses of sterically hindered zwitterionic pyridinium phe...

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Novel synthesis of 3, 5-disubstituted pyridines by 1, 4-cycl...

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Detail Synthetic Route


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