Natural product communications 2015-11-01

Ruta graveolens Extracts and Metabolites against Spodoptera frugiperda.

Benjamin A Ayil-Gutiérrez, Jesús M Villegas-Mendoza, Zuridai Santes-Hernndez, Alma D Paz-González, Maribel Mireles-Martínez, Ninfa M Rosas-García, Gildardo Rivera

Index: Nat. Prod. Commun. 10 , 1955-8, (2016)

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Abstract

The biological activity of Ruta graveolens leaf tissue extracts obtained with different solvents (ethyl acetate, ethanol, and water) and metabolites (psoralen, 2- undecanone and rutin) against Spodoptera frugiperda was evaluated. Metabolites levels in extracts were quantified by HPLC and GC. Ethyl acetate and ethanol extracts showed 94% and 78% mortality, respectively. Additionally, psoralen metabolite showed a high mortality as cypermethrin. Metabolite quantification in extracts shows the presence of 2-undecanone (87.9 µmoles mg(-1) DW), psoralen (3.6 µmoles mg(-1) DW) and rutin (0.001 pmoles mg(-1) DW). We suggest that these concentrations of 2-undecanone and psoralen in R. graveolens leaf tissue extracts could be responsible for S. frugiperda mortality.