PLoS ONE 2012-12-01

In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells.

Rainer Ritz, Christian Scheidle, Susan Noell, Florian Roser, Martin Schenk, Klaus Dietz, WolfgangSL Strauss

Index: PLoS ONE 7(12) , e51974, (2012)

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Abstract

Hypericin (HYP) is a naturally occurring photosensitizer. Cellular uptake and photodynamic inactivation after incubation with this photosensitizer have neither been examined in medulloblastoma cells in vitro, nor compared with 5-aminolevulinic acid-derived protoporphyrin IX (5-ALA-derived PpIX).