Clinica Chimica Acta 1979-06-15

The occurrence of gamma-glutamylphenylalanine in the urine of newborn phenylketonurics.

H Peck, R J Pollitt

Index: Clin. Chim. Acta 94(3) , 237-40, (1979)

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Abstract

The urine of untreated phenylketonurics in the first weeks of life contains gamma-glutamylphenylalanine (0.07--0.69 mmol/g creatinine, 12 samples) visible on the normal 2-dimensional electrophoreto-chromatogram. This compound is less prominent or absent when urine from older untreated phenylketonurics is examined and is not seen in normal urine.