Chemical Communications 2012-09-25

Rhodium acetate/base-catalyzed N-silylation of indole derivatives with hydrosilanes.

Shintaro Itagaki, Keigo Kamata, Kazuya Yamaguchi, Noritaka Mizuno

Index: Chem. Commun. (Camb.) 48(74) , 9269-71, (2012)

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Abstract

In the presence of Rh(2)(OAc)(4) (OAc = acetate) and TBA(2)WO(4) (TBA = tetra-n-butylammonium), the N-silylation of indole derivatives with hydrosilanes efficiently proceeded to give the corresponding N-silylated indoles in high yields. Pyrrole and carbazole were also N-silylated with the combined catalysts.