Tetrahedron: Asymmetry

Sc (BINOL) 2 Li: a new heterobimetallic catalyst for the asymmetric Strecker reaction

M Chavarot, JJ Byrne, PY Chavant, Y Vallée

Index: Chavarot, Murielle; Byrne, Janice J.; Chavant, Pierre Y.; Vallee, Yannick Tetrahedron Asymmetry, 2001 , vol. 12, # 8 p. 1147 - 1150

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Citation Number: 98

Abstract

The new chiral heterobimetallic complex Sc (BINOL) 2Li 1 was prepared and used as a catalyst in the enantioselective addition of a cyanide source (HCN or TMSCN) to several imines. High conversion rates and enantiomeric excesses (ees) as high as 95% were obtained.