Tetrahedron: Asymmetry

Sc (BINOL) 2 Li: a new heterobimetallic catalyst for the asymmetric Strecker reaction

M Chavarot, JJ Byrne, PY Chavant, Y Vallée

文献索引：Chavarot, Murielle; Byrne, Janice J.; Chavant, Pierre Y.; Vallee, Yannick Tetrahedron Asymmetry, 2001 , vol. 12, # 8 p. 1147 - 1150

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被引用次数: 98

摘要

The new chiral heterobimetallic complex Sc (BINOL) 2Li 1 was prepared and used as a catalyst in the enantioselective addition of a cyanide source (HCN or TMSCN) to several imines. High conversion rates and enantiomeric excesses (ees) as high as 95% were obtained.