Phytochemistry

Tiglicamides A–C, cyclodepsipeptides from the marine cyanobacterium Lyngbya confervoides

S Matthew, VJ Paul, H Luesch

Index: Matthew, Susan; Paul, Valerie J.; Luesch, Hendrik Phytochemistry, 2009 , vol. 70, # 17-18 p. 2058 - 2063

Full Text: HTML

Citation Number: 18

Abstract

The Floridian marine cyanobacterium Lyngbya confervoides afforded cyclodepsipeptides, termed tiglicamides A–C (1–3), along with their previously reported analogues largamides A– C (4–6), all of which possess an unusual tiglic acid moiety. Their structures were deduced by one-and two-dimensional NMR combined with mass spectrometry and the absolute configurations established by chiral HPLC and Marfey's analysis of the degradation ...