Grignard reactions in pyridinium and phosphonium ionic liquids

…, F Atefi, RD Singer, PJ Scammells

Index: Ford, Leigh; Atefi, Farzad; Singer, Robert D.; Scammells, Peter J. European Journal of Organic Chemistry, 2011 , # 5 p. 942 - 950

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Citation Number: 9

Abstract

Abstract Alkylpyridinium (10a, R= Me and 10b, R= Et) and tetraalkylphosphonium (19) ionic liquids which possess ether functionality were prepared and evaluated as solvents and co- solvents for Grignard reactions. Interestingly, reduction of the starting aldehydes to the corresponding primary alcohol was the favored pathway when reactions were conducted in pyridinium ILs 10a, b in the absence an ethereal co-solvent. However, the same reactions ...