e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Stereospecific Reactions of Nucleophilic Agents with Acetylenes and Vinyl-type Halides. VII. The Mechanism of the Base-catalyzed Reaction of Trichloroethylene with …
WE Truce, R Kassinger
Index: Truce; Kassinger Journal of the American Chemical Society, 1958 , vol. 80, p. 1916,1918, 1919
Previous work in this Laboratory2,* has indicated that reactions of nucleophilic agents with halogenated ethylenes may proceed by at least two different mechanisms,;. e., either initial p- elimination to form an acetylenic intermediate followed by nucleophilic addition, or initial nucleophilic addition to form a saturated intermediate or an incipient carbanion followed by elimination of HX or X-, respectively. Which path is followed will be determined in large ...