Trifluopromazine chlorine atom by other groups and/or the dimethylamino group by piperazine moieties; eg, compounds 5-gj3 Table I. The pharmacology of some of these compounds has been reviewed by Viaud. 2 As part of an extensive investigation of the structural requirements for effective tranquilizing and antiemetic activities in this class of compounds, we prepared a series of analogs of the phenothiazine derivatives, listed ...