Catalyst??Free Dehydrative α??Alkylation of Ketones with Alcohols: Green and Selective Autocatalyzed Synthesis of Alcohols and Ketones

…, J Chen, H Tian, X Yuan, S Li, C Zhou…

Index: Xu, Qing; Chen, Jianhui; Tian, Haiwen; Yuan, Xueqin; Li, Shuangyan; Zhou, Chongkuan; Liu, Jianping Angewandte Chemie - International Edition, 2014 , vol. 53, # 1 p. 225 - 229 Angew. Chem., 2014 , vol. 126, # 1 p. 229 - 233,5

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Citation Number: 36

Abstract

Abstract Direct dehydrative α-alkylation reactions of ketones with alcohols are now realized under simple, practical, and green conditions without using external catalysts. These catalyst- free autocatalyzed alkylation methods can efficiently afford useful alkylated ketone or alcohol products in a one-pot manner and on a large scale by C [DOUBLE BOND] C bond formation of the in situ generated intermediates with subsequent controllable and ...