Advanced Synthesis & Catalysis

Aldehyde??Catalyzed Transition Metal??Free Dehydrative β??Alkylation of Methyl Carbinols with Alcohols

Q Xu, J Chen, Q Liu

Index: Xu, Qing; Chen, Jianhui; Liu, Quan Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 697 - 704

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Citation Number: 24

Abstract

Abstract Different to the borrowing hydrogen strategy in which alcohols were activated by transition metal-catalyzed anaerobic dehydrogenation, the direct addition of aldehydes was found to be an effective but simpler way of alcohol activation that can lead to efficient and green aldehyde-catalyzed transition metal-free dehydrative C-alkylation of methyl carbinols with alcohols. Mechanistic studies revealed that the reaction proceeds via in situ formation ...