The reaction of indole derivatives with cyanoacetic acid followed by treatment with DMFDMA gave the intermediate indolyl enaminonitriles (3). Further reaction with aminoguanidine yielded 5＇-cyanomeridianin analogues (4). The same intermediate reacted with p- methoxyphenylhydrazine to give the pyrazolyl derivative (8). Treatment of (2E)-3- dimethylamino-2-(1H-indol-3-yl)-propenoate (3a) with hydroxylamine hydrochloride in ...
