Synthesis of 3-indolylazoles and meridianin derivatives from indolyl enaminonitriles

…, AM Salaheldin, FAA Paz, LM Rodrigues

文献索引：Oliveira-Campos, Ana M. F.; Salaheldin, Abdellatif M.; Paz, Filipe A. Almeida; Rodrigues, Ligia M. Arkivoc, 2011 , vol. 2011, # 11 p. 121 - 133

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被引用次数: 3

摘要

The reaction of indole derivatives with cyanoacetic acid followed by treatment with DMFDMA gave the intermediate indolyl enaminonitriles (3). Further reaction with aminoguanidine yielded 5＇-cyanomeridianin analogues (4). The same intermediate reacted with p- methoxyphenylhydrazine to give the pyrazolyl derivative (8). Treatment of (2E)-3- dimethylamino-2-(1H-indol-3-yl)-propenoate (3a) with hydroxylamine hydrochloride in ...