e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Regiospecific synthesis of terminal, oxyfunctionalized methyl ketone enamines via catalytic aminomercuriation of prop-2-ynyl esters and ethers
J Barluenga, F Aznar, R Liz, C Postigo
Index: Barluenga, Jose; Aznar, Fernando; Liz, Ramon; Postigo, Carmen Journal of the Chemical Society, Chemical Communications, 1986 , # 19 p. 1465 - 1467
Catalytic aminomercuriation of 1-substituted prop-2-ynyl esters and ethers (5) provides a mild, simple, and regiospecific route to the terminal functionalized enamines (6) despite the fact that they are potentially isomerisable to their internal form; hydrolysis of (6) furnishes α- oxyketones (7).