e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Studies on organosilicon chemistry. 98. Synthesis and consecutive double alkylation reactions of (2-siloxyallyl) silanes as the synthetic equivalent of acetone. alpha.,. …
Summary:(2-Siloxyally1) silanes as the synthetic equivalent of tandem acetone apt-dianion, readily prepared by quenching of the enolate of a-(trimethylsily1) acetone with chlorosilanes or by 1, 3 C-0 Si shift of bis (organosily1)-acetone, react with various electrophiles promoted by a Lewis acid to give the corresponding a, a'-disubstituted acetones.