Nouvelle voie de synthèse d'isoindolones et d'isoquinoléines par condensation d'iminophosphoranes avec l'ortho-phtalaldéhyde: réactions, mécanismes et …

T Aubert, M Farnier, R Guilard

Index: Aubert, Thierry; Farnier, Michel; Guilard, Roger Canadian Journal of Chemistry, 1990 , vol. 68, # 6 p. 842 - 851

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Citation Number: 13

Abstract

The condensation of various iminophosphoranes with o-phthalaldehyde led directly to N- substituted isoindoline-1-ones and 3-acylisoquinolines. Three different mechanisms, depending on the nature of the iminophosphorane and reaction conditions, are proposed. All the compounds have been fully characterized, particularly by one-and two-dimensional nuclear magnetic resonance spectroscopy. Key words: isoindolones, isoquinolines, ...