Pharmaceutical Chemistry Journal

Method of preparation of pyrrolo [3, 2-d] pyrimidine (9-desazapurine) and its 4-oxo-3, 4-dihydro derivative (9-desazahypoxanthine)

LV Éktova, MN Preobrazhenskaya

Index: Ektova, L. V.; Preobrazhenskaya, M. N. Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 7 p. 572 - 574 Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 7 p. 860 - 863

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Abstract

One of the relatively readily available starting compounds for the preparation of substituted pyrrolo [3, 2-d] pyrimidines is 4-oxo-3, 4-dihydro-7-formylpyrrolo [3, 2-d] pyrimidine (I), which was obtained by reacting a Vilsmeier reagent with 4-oxo-5-amino-6-methyl-3, 4-

~79%

~81%

Development of a practical synthesis of a purine nucleoside ...

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Pyrrolo [3, 2-d] pyrimidines. IV. Synthesis and antibacteria...

[Pharmaceutical Chemistry Journal, , vol. 16, # 11 p. 834 - 838 Khimiko-Farmatsevticheskii Zhurnal, , vol. 16, # 11 p. 1338 - 1343]