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Pharmaceutical Chemistry Journal

Method of preparation of pyrrolo [3, 2-d] pyrimidine (9-desazapurine) and its 4-oxo-3, 4-dihydro derivative (9-desazahypoxanthine)

LV Éktova, MN Preobrazhenskaya

文献索引:Ektova, L. V.; Preobrazhenskaya, M. N. Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 7 p. 572 - 574 Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 7 p. 860 - 863

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被引用次数: 0

摘要

One of the relatively readily available starting compounds for the preparation of substituted pyrrolo [3, 2-d] pyrimidines is 4-oxo-3, 4-dihydro-7-formylpyrrolo [3, 2-d] pyrimidine (I), which was obtained by reacting a Vilsmeier reagent with 4-oxo-5-amino-6-methyl-3, 4-