Chemical and pharmaceutical bulletin

Facile synthesis of 9-substituted 9-deazapurines as potential purine nucleoside phosphorylase inhibitors.

H Shih, HB Cottam, DA Carson

Index: Chemical and pharmaceutical bulletin, , vol. 50, # 3 p. 364 - 367

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Citation Number: 11

Abstract

... 2002 Pharmaceutical Society of ... The chemistry of 3 toward the Friedel–Crafts acylation or alkylation was expected to be the same as 1. Accordingly, 9-benzoyl-9-deazahypoxanthine (21), 9-(3,4-dichlorobenzoyl)-9 ... Experimental All solvents and chemicals were of analytical grade ...