Synthesis

Simple and improved procedure for the regioselective acylation of aromatic ethers with carboxylic acids on the surface of graphite in the presence of methanesulfonic …

MH Sarvari, H Sharghi

Index: Sarvari, Mona Hosseini; Sharghi, Hashem Synthesis, 2004 , # 13 p. 2165 - 2168

Full Text: HTML

Citation Number: 16

Abstract

Abstract Friedel-Crafts acylation of aromatic compounds such as anisole has been successfully carried out using the combination of graphite with MeSO 3 H. Both aromatic and aliphatic carboxylic acids reacted smoothly under the conditions to afford the corresponding aromatic ketones in high yield.